42 - Live world record DNA Sequence Mapping

On 12/12, in less than three days, GENALICE will impress the world of biomedical science. During a 24 hours live webcast we will map the sequences of 42 full human genomes on a simple dual Intel E5 server. A live registration and showcase of the stellar performance on speed and accuracy and the global online launch event of our groundbreaking new software solution GENALICE MAP. Based on the performance of all known competitors it is expected to be a new unofficial world record. For the most widely used tool, Burrows-Wheeler Aligner (BWA), it takes up to three full days to map just one full human genome on the same hardware configuration. For patients with complex diseases DNA profiles add significant value to the development of new personalized medicines and diagnosis and treatment. To bring this value to the clinic, software solutions play an important role. Sequencing machines digitize DNA of patients. Those sequencers produce short reads of DNA. Software tools are needed to map them in the right order and build personal DNA profiles. Correlations between DNA profiles and other biomedical and clinical data from these patients lead to the discovery of biomarkers. These can in turn be used to develop personalized medicines. A biomarker database can be used in the clinic to improve diagnosis and guide targeted individual patient treatment. This is anticipated to provide a significant leap forward in the treatment of complex diseases: much higher success rates and with far less adverse effects.

Fuente : http://www.alphagalileo.org/ViewItem.aspx?ItemId=1...