Development of a novel dual JAK/Src kinase inhibitor

Inhibitors of both JAK and Src kinases represent promising targets for cancer therapeutics because of the central importance of these kinases in tumor cell proliferation and survival. This research article by Liu et al. describes MLS-2384 which is a synthetic derivative of amarine natural product, 6-bromoindirubin-3-oxime.

Fuente : http://www.eurekalert.org/pub_releases/2014-01/lb-...