How 'phenotype switching' can make melanoma become metastatic and resistant to drugs

One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body. Wistar researchers describe how melanoma tumors use "phenotype switching" -- changing their outward appearance -- can result in melanoma cells that are highly invasive and more resistant to therapy.

Fuente : http://www.eurekalert.org/pub_releases/2013-10/twi...