PD-like sleep and motor problems observed in α-synuclein mutant mice

In the quest for an animal model of Parkinson's disease that mimics motor and non-motor symptoms of human PD, scientists have developed strains of mice that overexpress α-synuclein. By studying a strain of mice bred to overexpress α-synuclein via the Thy-1 promoter, scientists have found these mice develop many of the age-related progressive motor symptoms of PD and demonstrate changes in sleep and anxiety. Their results are published in the latest issue of Journal of Parkinson's Disea...

Fuente : http://www.eurekalert.org/pub_releases/2013-06/ip-...